Friday, May 31, 2013

Syrian rebels need heavy weapons, McCain says

WASHINGTON (AP) ? Syrian rebels battling the forces of President Bashar Assad must receive ammunition and heavy weapons to counter the regime's tanks and aircraft or it will be impossible for them to prevail Sen. John McCain said days after he quietly slipped into Syria to meet with the opposition.

"They just can't fight tanks with AK-47s," McCain said Friday in a telephone interview.

The Republican lawmaker and 2008 presidential candidate made an unannounced visit to Syria on Monday, traveling across the border near Kilis, Turkey, and spending about two hours meeting with rebel leaders. McCain has been one of the most vocal lawmakers demanding aggressive U.S. military action in the 2-year-old Syrian civil war, calling for establishment of a no-fly zone and arming the rebels.

The Obama administration has been reluctant to provide weapons to the disparate opposition, fearing that they will fall into the wrong hands in a volatile region. McCain said he discussed what types of weapons the rebels need and whether they could ensure their control.

"I'm confident that they could get the weapons into the right hands and there's no doubt that they need some kind of capability to reverse the battlefield situation, which right now is in favor of Assad," McCain said.

McCain, a member of the Armed Services and Foreign Relations committees, was the first U.S. senator to travel to Syria since the civil war began more than two years ago. He said he worked with Deputy Secretary of State William Burns in arranging the trip.

McCain said he spoke with Secretary of State John Kerry "a couple of times. It wasn't that I was hiding it from him; it just didn't seem to come up. I thought Burns was the right guy to go through. They were very important in the trip. We couldn't have done it without their cooperation."

Gen. Salim Idris, chief of the Supreme Military Council of the Free Syrian Army, accompanied McCain and they met with 19 battalion commanders.

Citing the photo of McCain's meeting, a Lebanese newspaper has reported that McCain unwittingly crossed paths with two men connected to a rebel group responsible for the kidnapping of 11 Lebanese Shiite pilgrims in 2012. McCain said one of the men he reportedly met with is dead and no one in his meeting was identified as the other.

"The people I met with and talked to directly were well-vetted. Their names and their duties were outlined to me. They came from all over Syria," he said.

Two years of violence in Syria have killed more than 70,000 people, according to the United Nations. President Barack Obama has demanded that Assad give up power, while Russia has stood by Syria, its closest ally in the Arab world. Russian officials have said they will support anti-aircraft systems to Syria, and Assad suggested on Thursday that he had received the first shipment.

The United States and Russia are trying to get the Syrian government and opposition forces into peace negotiations. Those talks, initially planned for Geneva next month, have been delayed until July at the earliest.

"It's hard to imagine Bashar Assad negotiating his departure when he has the upper hand on the battlefield," McCain said. "I'm all for a conference, but I think that conference should take place when Bashar Assad knows that he is doomed to defeat if he doesn't negotiate."

Last week, the Senate Foreign Relations Committee voted to provide weapons to rebels in Syria, as well as military training to vetted rebel groups and sanctions against anyone who sells oil or transfers arms to the Assad regime.

The European Union decided late Monday to lift the arms embargo on the Syrian opposition while maintaining all other sanctions against Assad's regime after June 1, British Foreign Secretary William Hague said.

Source: http://news.yahoo.com/mccain-syrian-rebels-heavy-weapons-190000613.html

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'After Earth' leaves critics cold ahead of competitive weekend

By Piya Sinha-Roy

LOS ANGELES (Reuters) - Will Smith may be one of Hollywood's most bankable action stars, but his new film, "After Earth," in which he stars with his 14-year-old son Jaden, has opened to cold reviews from critics and faces stiff competition in a busy box office weekend.

"After Earth" is a futuristic post-apocalyptic tale of a father and his teenage son in which the young boy must embark on a life-saving mission.

Sony Pictures Entertainment, a division of Sony Corp., spent about $130 million to produce the movie, making it one of the studio's biggest summer releases.

The story is centered on the father-son relationship and the dynamic of a father passing the mantle to his son is mirrored both on screen and off, as the younger Smith leads the action.

Will Smith, 44, who wrote the initial story and was the executive producer of the film, said the project gave him valuable time to spend with his son, with whom he first starred in the 2006 family drama, "The Pursuit of Happyness."

"Filmmaking and entertainment is our family business," Smith said at a recent news conference. "So, it really gave us an opportunity for the last year to spend ten or twelve hours a day together, every day. And for me it's just the best way, for me at least, to parent."

Jaden Smith bears a strong resemblance to his famous father and won over most critics as the lead in 2010's reboot of "The Karate Kid." However, he has not been received as warmly for his performance as ranger Kitai Raige in "After Earth."

NEGATIVE REVIEWS

Variety's Scott Foundas said both father and son failed to meet expectations. "Senior Smith gives one of the least substantive performances of his career, while the undeniably charismatic Jaden toggles between ... paralyzing fear and simmering rage."

Manohla Dargis wrote in the New York Times that the younger Smith was "a pretty teenager with jumpy eyebrows whose character remains an insufferable brat."

Rolling Stone's Peter Travers slammed the script as "an unholy mess of platitudes and posturing." He gave the film one out of five stars, saying "It's not a good sign when you sit there thinking one thing - Make. It. Stop."

"After Earth" scored just 32 out of 100 on Metacritic.com, which compiles ratings based on critics' reviews. Only 13 percent of critics recommended the movie in reviews collected on the Rotten Tomatoes website.

This is despite the fact that the film was directed by M. Night Shayamalan, who scored a huge hit with the 1999 suspense drama "The Sixth Sense," which grossed more than $672 million at the worldwide box office. Shayamalan was less successful though with 2006's "Lady in the Water" and 2010's "The Last Airbender."

Box office forecasters predict "After Earth" will make $35- $40 million in U.S. and Canadian ticket sales from Friday through Sunday.

The film opened on Thursday and took in $1 million at U.S. and Canadian theaters, behind Lions Gate Entertainment's comedy heist caper "Now You See Me," which earned $1.5 million.

"After Earth" faces tough competition this weekend from recent releases still drawing big business, such as car-chase sequel "Fast & Furious 6," superhero tale "Iron Man 3," and sci-fi film "Star Trek Into Darkness."

"It's not an enviable task opening up this weekend," said Phil Contrino, chief analyst with Boxoffice.com. International sales will be critical, he said, since Will Smith remains a big draw for overseas audiences.

Sony Pictures spokesman Steve Elzer said a weekend take of about $30 million in the United States and Canada would be a solid number for a movie that is not a branded sequel.

Sony's other upcoming summer films include action thriller "White House Down," sci-fi adventure "Elysium," and book adaptation "The Moral Instruments: City of Bones."

(Additional reporting by Lisa Richwine and Reuters TV; Editing by David Brunnstrom)

Source: http://news.yahoo.com/earth-leaves-critics-cold-ahead-competitive-weekend-222954407.html

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Tuesday, May 14, 2013

This Simple Device Makes Glorious Timelapses Easy?Even at Night

If the term intervalometer leaves you scratching your head, but you have the perfect idea for the next viral timelapse video, Brinno's here to help. The company's new TLC200 Pro makes creating timelapses as easy as using a point-and-shoot camera. And thanks to a relatively large, extra-sensitive 1/3-inch sensor, it will capture beautiful results even when left filming over night.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/XeTRJ1Ma-Wo/this-simple-device-makes-glorious-timelapses-easy-even-504505621

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Saturday, May 4, 2013

'Mockingbird' author Lee sues over copyright in NY

NEW YORK (AP) ? Harper Lee, who wrote the Pulitzer Prize-winning novel "To Kill a Mockingbird," filed a lawsuit Friday to re-secure the copyright to it.

The lawsuit filed in federal court in Manhattan seeks unspecified damages from the son-in-law of Lee's former literary agent and companies he allegedly created.

The lawsuit alleges the son-in-law, Samuel Pinkus, failed to properly protect the copyright of the book after his father-in-law, Eugene Winick ? who had represented Lee as a literary agent since the book was published in 1960 through the firm McIntosh and Otis ? became ill a decade ago. The 87-year-old author alleges Pinkus took advantage of her declining hearing and eyesight seven years ago to get her to assign the book's copyright to him and a company he controlled.

Lee, who lives in Monroeville, Ala., has taken legal action to get the copyright reassigned but alleges Pinkus still received commissions.

"The transfer of ownership of an author's copyright to her agent is incompatible with her agent's duty of loyalty; it is a gross example of self-dealing," the lawsuit says.

The former agent's son-in-law didn't immediately return a call seeking comment.

"To Kill a Mockingbird" won the Pulitzer for fiction and is widely assigned in schools. The film version won three Academy Awards.

Source: http://news.yahoo.com/mockingbird-author-lee-sues-over-copyright-ny-225024166.html

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Saturday, April 20, 2013

Managing Communications on the Go | The Marketing Department

Today?s companies have more ways than ever to connect and engage with potential buyers, and that connectivity is fueling demand for marketing services. In fact, a study last year found that total communications spending, including marketing, advertising, and communications, was expected to grow 5.6% and reach nearly $1.2 trillion in 2012.

The ever-expanding presence of mobile devices and social media among customers and in the workplace has added marketing communications channels, dramatically affecting the marketing industry. The resulting demand for responsive communications makes it critical to find both efficient and cost-effective ways to quickly respond to customers, clients, and staff, especially while on the go.

One solution, particularly for smaller businesses, is a virtual phone system. With it, marketing professionals can have peace of mind that a client can always reach them, whether they?re in the office or not.

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Marketing professionals can use their mobile phones to maintain efficiency on the go and professionally manage day-to-day communication demands by applying the following tips and features:

1. Office in the Cloud

The modern office is no longer defined by walls and cubicles. Your business and your customers are on the move, and mobile phones are even more important than ever.

A cloud-based phone system can turn your smartphone into a complete mobile office with features such as call routing, call screening, multiple extensions, personalized greetings, voice to text, and more.

With professional greetings and menus, callers are handled proficiently, and your calls are routed to wherever you are?cell phone, home, or office?24/7.

2. Voicemail?a Terrible Thing to Waste

Whether you?re in a meeting or driving back to the office, juggling the busy demands of the day can make it difficult to answer every call.

Get ?voice to text? so voicemails are transcribed to a text message or email, allowing you to read them as they roll in rather than dialing into a cumbersome voicemail system.

Being able to discreetly peek at voice messages while in a meeting can help you stay connected to the needs of customers and team members in real time.

3. A Faster Response to Campaigns

Using unique phone numbers to track advertising campaigns is an established tactic of big-budget marketers. Access to an endless supply of new phone numbers, paired with the ability to easily forward those calls and generate campaign reports, is now possible for smaller companies. Marketers can now quickly and affordably identify the best sources of traffic and use that data to drive more ROI from their campaigns.

4. Real-time Collaboration

Motivate teams, customers, and vendors to action with Web conferencing. Using easy-to-initiate online meetings, you can collaborate with remote team members, give sales pitches, or meet with clients without the extra time or cost of lengthy travel.

Web conferencing allows you to turn your desktop or laptop into a mobile conference room, enabling you to maintain clear and efficient communication regardless of your location.

5. Brand Enhancement

Your phone system makes a strong statement about your brand. Whether you are a business of one or of many, a professionally recorded greeting message and an auto attendant can maximize the impression of professionalism with customers and further the credibility of your brand.

Make it easier for people to find you by providing one central toll-free phone number that can route to multiple devices. Even better, an 800 number makes your business seem even bigger than it may be, as well as highly professional, even if you happen to be working from home or the road.

6. Extending Your Reach

Technology has eliminated the barriers of geographic location. A toll-free business phone number gives your marketing business a nationwide presence and the credibility associated with large, well-established companies. Meanwhile, using local phone numbers across the country can help marketers reach new customers in targeted markets with easily recognizable prefixes.

7. Going VoIP and Saving Money

A mobile VoIP app can automatically transfer calls from your network carrier to the Internet whenever WiFi is available. With this feature, you can save precious mobile minutes and not have to worry about data charges. It can also help you stay connected in dead service zones or very rural areas, so you don?t miss a call.

Source: http://themarketingdepartment.aw/2013/04/18/managing-communications-on-the-go/

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Tuesday, April 16, 2013

Gene signature can predict who will survive chemotherapy

Apr. 16, 2013 ? An eight gene 'signature' can predict length of relapse-free survival after chemotherapy, finds new research in Biomed Central's open access journal BMC Medicine.

Researchers from Academia Sinica and the National Taiwan University College of Medicine first identified genes that were involved in cellular invasion, a property of many cancer cells, using the National Cancer Institute's 60 human cancer cell line panel (NCI-60). Comparing the pattern of activation of each of these genes in different cell lines with how these cell lines responded to 99 different anti-cancer drugs, helped narrow down the list of genes to just those which could potentially influence the outcome of chemotherapy.

Testing this link, Prof Ker-Chau Li, from Academia Sinica and UCLA, commented, "Our study found eight genes which were involved in invasion, and the relative activation of these genes correlated to chemotherapy outcome, including the receptor for growth factor EGF. We also found that some invasion genes had unique patterns of expression that reflect the differential cell responses to each of the chemotherapy agents -- five drugs (paclitaxel, docetaxel, erlotinib, everolimus and dasatinib) had the greatest effect."

When the researchers looked at gene expression data of these eight genes from cancer cell lines they found that there was an obvious difference between cells which responded to chemotherapy and those who did not (albeit with some overlap). In clinical studies, looking at lung and breast cancer, the patients, whose gene signature put them in the low-risk group, had a longer relapse free survival than the high-risk group.

Prof Pan-Chyr Yang of National Taiwan University added, "The discovery of prognostic biomarkers for chemotherapy patients remains critical toward improving the efficacy of cancer treatment. The eight-gene signature obtained here may help choice of treatment as part of individualized cancer therapy and our method of gene discovery may be applicable in studying other cancers."

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Story Source:

The above story is reprinted from materials provided by BioMed Central Limited, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Yi-Chiung Hsu, Hsuan-Yu Chen, Shinsheng Yuan, Sung-Liang Yu, Chia-Hung Lin, Guani Wu, Pan-Chyr Yang and Ker-Chau Li. Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity. BMC Medicine, 2013 DOI: 10.1186/1741-7015-11-106

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/a1PPqF_ZleE/130415204819.htm

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